In vivo anti-inflammatory and in vitro antioxidant activities of Moroccan medicinal plants |
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Authors: | Moussaid Mina Elamrani Abd Elaziz Bourhim Nourdinne Benaissa Mohamed |
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Affiliation: | Department of Chemistry, Hassan II University, Casablanca, Morocco 20 100. noune_moussaid@yahoo.fr |
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Abstract: | Five ethanol extracts of wild plants from the Casablanca region (Morocco) used in local traditional medicine for the treatment of inflammatory diseases were evaluated for their in vivo topical anti-inflammatory activity (inhibition of carrageenan-induced ear edema in mice) and in vitro antioxidant and antiradical properties (inhibition of linoleic acid oxidation, DPPH radical scavenging). All the extracts showed an anti-inflammatory effect: 300 microg/cm2 provoked edema reductions ranging from 22 to 28%. All the extracts also exerted radical scavenging and/or antioxidant properties, the most active plant being Mentha pulegium L. (Lamiaceae), which contained the highest amount of phenolics (339 mg/g), and flavonoids (16.7 mg/g). |
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