Amplexicine, an antioxidant flavan-3-ol from Polygonum amplexicaule |
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| Authors: | Tantry Mudasir A Rahman Aziz A |
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| Institution: | National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University 38677 MS, USA. mtantry@olemiss.edu |
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| Abstract: | Bioassay guided fractionation of an ethanolic extract of Polygonum amplexicaule D. Don led to the isolation of amplexicine, a new flavan-3-ol (1), along with khellactone (2). The structure of the isolates was established by UV, IR, HRESI/MS and NMR, including 1D and 2D experiments. Compound 1 exhibited considerable antioxidant activity in a 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging assay. |
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