Temperature dependence of a Ce3+ doped SiO2 radioluminescent dosimeter for in vivo dose measurements in HDR brachytherapy |
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| Affiliation: | 1. Medical Physics Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy;2. Dept. of Physics, Università degli Studi of Milano and INFN, Milan, Italy;3. Radiation Oncology 2 Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy;4. Dept. of Materials Science, Università degli Studi di Milano-Bicocca, Milan, Italy;1. Department of Physics, King Mongkut''s University of Technology Thonburi, Bangkok, 10140, Thailand;2. New Industry Creation Hatchery Center, Tohoku University, Sendai, Miyagi, 980-8579, Japan;3. Institute for Materials Research, Tohoku University, Sendai, Miyagi, 980-8577, Japan;4. Institute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University in Torun, ul. Grudziadzka 5, 87-100, Torun, Poland;5. Institute of Physics, AS CR, Cukrovarnicka 10, 16253, Prague, Czech Republic;1. Universidade Federal de Sergipe, Departamento de Física, Av. Marechal Rondon, s/n – Jd. Rosa Elze, 50740-540 São Cristóvão, SE, Brazil;2. Universidade Federal de Uberlândia, Instituto de Física, Laboratório de Novos Materiais Isolantes e Semicondutores (LNMIS), Uberlândia, MG, Brazil;3. Instituto de Pesquisas Energéticas e Nucleares, Comissão Nacional de Energia Nuclear, IPEN-CNEN, São Paulo, Brazil;4. Università di Pisa, Scuola di Ingegneria, Largo L. Lazzarino 2, Pisa I-56122, Italy;5. Yale University, School of Medicine, PO Box 208042, New Haven, CT 06520-8042, United States;1. Physics, Inter-Curricular Courses Department, Çankaya University, 06530 Ankara, Turkey;2. Department of Electrical and Electronics Engineering, Atilim University, 06836 Ankara, Turkey;3. Department of Physics, Baku State University, 1148 Baku, Azerbaijan;4. Department of Physics, Middle East Technical University, 06800 Ankara, Turkey;5. Virtual International Scientific Research Centre, Baku State University, 1148 Baku, Azerbaijan;1. Fiber Optics Research Center, Faculty of Engineering, Multimedia University, Cyberjaya, Malaysia;2. Clinical Oncology Unit, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia;3. Telekom Malaysia Research & Development Sdn. Bhd., Malaysia;4. Department of Chemistry, Faculty of Science, University of Malaya, Malaysia;5. Health Physics Division, Atomic Energy Centre, Bangladesh Atomic Energy Commission, 4 Kazi Nazrul Islam Avenue, Shahbag, Dhaka 1000, Bangladesh;6. Sunway University, Institute for Healthcare Development, 46150 PJ, Malaysia;7. Department of Physics, University of Surrey, Guildford GU2 7XH, UK |
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| Abstract: | Fiber-optic-coupled scintillation dosimeters are characterized by their small active volume if compared to other existing systems, and are therefore particularly suited for internal in vivo dosimetry. Due to possible differences between calibration conditions (i.e., room temperature) and conditions of clinical application (i.e., body temperature), their temperature dependence should be accurately studied. In this work, the temperature dependence of a Ce3+ doped SiO2 scintillation detector coupled to a SiO2 optical fibre was investigated for high dose rate brachytherapy applications. To this aim, two sets of irradiations with two different Ir-192 sources were performed in a water bath phantom at water temperatures ranging between 17 °C and 40.4 °C (Experiment 1). The relative response of the dosimeter was collected and analyzed. The same experiment was repeated with a second optical fibre which was designed without the active Ce3+ doped part at its end (Experiment 2) as well as by changing the length of the passive fibre inserted in water (Experiment 3). The two sets of measurements of experiment 1 were in accordance, indicating a linear increase with temperature of the scintillator sensitivity, with an average increase of 0.27 ± 0.2%/°C. In experiment 2, a 0.5%/°C increase of the collected signal resulted for the passive fibre. No significant difference of the temperature coefficient was found by changing the length of the fibre inserted in water (experiment 3). The obtained results show that a temperature-specific correction factor should be adopted at temperatures different than room temperature (e.g. for in vivo internal dosimetry). Further studies are required to understand the observations. |
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| Keywords: | HDR brachytherapy In vivo dosimetry Temperature dependence Scintillation dosimeter |
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