Morphology of synthetic DOPA-eumelanin deposited on glass and mica substrates: An atomic force microscopy investigation |
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| Institution: | 1. Department of Physics, Jadavpur University, Kolkata, 700032 West Bengal, India;2. RCSDS Reactor Control Division (Complex), Bhabha Atomic Research Centre, Mumbai, 400085 Maharashtra, India;1. Institute of Cellular and System Medicine, National Health Research Institutes, Maioli 350, Taiwan;2. Nursing Department of Yuanpei University, Xiangshan, Hsinchu 300, Taiwan;3. Department of Veterinary Medicine, College of Veterinary Medicine, National Chung Hsing University, Taichung 402, Taiwan;4. Graduate Institute of Metabolism and Obesity Sciences, College of Nutrition, Taipei Medical University, Taipei 110, Taiwan;5. Division of Animal Resources, Animal Technology Laboratories, Agricultural Technology Research Institute, Xiangshan, Hsinchu 300, Taiwan;6. Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan 701, Taiwan;7. Department of Science and Technology, Council of Agriculture, Executive Yuan, Taipei 100, Taiwan;1. Institute of Chemistry, University of Silesia, Katowice 40-006, Poland;2. Physics Department, College of Science, Aljouf University, P. O. Box 2014, Sakaka, Saudi Arabia;3. Physics Department, Faculty of Science, Ha''il University, P. O. Box 2440, 81451 Ha''il, Saudi Arabia;4. Laboratoire de Physique Quantique, Faculté des Sciences de Monastir, 5019 Monastir, Tunisia |
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| Abstract: | Bright field microscopy and atomic force microscopy techniques are used to investigate morphological properties of synthetic eumelanin, obtained by oxidation of l-DOPA solution, deposited on glass and mica substrates. Deposits of eumelanin are characterized by aggregates with different shape and size. On a micrometric scale, filamentous as well as granular structures are present on glass and mica substrates, with a larger density on the former than on the latter. On a nanometric scale, filamentous aggregates, several microns long and about 100 nm wide and high, and granular aggregates, ∼50 nm high and 100 nm wide, are found on both substrates, whereas point-like deposits less than 10 nm high and less than 50 nm wide are found on mica substrate. Dynamic light scattering measurements and atomic force microscopy images support the evidence that eumelanin presents only nanometric point-like aggregates in aqueous solution, whereas such nanoaggregates organize themselves according to granular and filamentous structures when deposition occurs, as a consequence of interactions with the substrate surface. |
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| Keywords: | Eumelanin Optical microscopy Atomic force microscopy Dynamic light scattering |
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