Reaction of 4-oxocarboxylic acids and 5-substituted 3<Emphasis Type="Italic">H</Emphasis>-furan-2-ones with 1,2-binucleophiles of aromatic and alicyclic series

Based on reactions of 5-substituted 3H-furan-2-ones or 4-oxocarboxylic acids with 1,2-binucleophiles of aromatic and aliphatic series methods were developed for the synthesis of tricyclic structures containing a pyrrolidine fragment fused with imidazolidine or oxazolidine ring. The pathways of the reactions are considered. It was demonstrated that the nature of the substrate did not affect the reaction direction, but changed the scheme of the interaction. The structures of compounds obtained for the first time were proved using IR and ¹H NMR spectra.