Syntheses of some analogs of a possible intermediate formed in the thymidylate synthetase reaction |
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Authors: | Daniel V. Santi |
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Abstract: | The syntheses of a number of analogs of a possible intermediate formed in the thymidylate synthetase reaction are described. These consist of a number of 5-arylaminomethyluracils (X) and N-methyl-N-[1,-(2′-deoxy-β-D-ribofuranosyl)thyminyl]-p-aminobenzoyl glutamic acid (XXb). |
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