Pyrrolizidine Alkaloids from Onosma leptantha |
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Authors: | Ourania Kretsi Nektarios Aligiannis AlexiosLeandros Skaltsounis IoannaB Chinou |
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Institution: | Ourania Kretsi,Nektarios Aligiannis,Alexios?Leandros Skaltsounis,Ioanna?B. Chinou |
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Abstract: | Three new pyrrolizidine alkaloids, leptanthine ( 2 ), its corresponding N‐oxide 1 , and N‐oxide of 3′‐O‐acetylechihumiline ( 3 ), were isolated from the aerial parts of Onosma leptantha, together with two known alkaloids of the same type, echihumiline ( 5 ) and echihumiline N‐oxide ( 4 ). Their structures and configurations were determined by chemical and spectroscopic methods, especially 1D and 2D NMR analyses, including long‐range 1H,15N correlations at natural abundance. |
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