Synthesis of novel 2‐amino‐1,3‐thiazole‐5‐carboxylates utilising ultrasonic and thermally mediated aminolysis |
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Authors: | Luke A. Baker Craig M. Williams |
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Abstract: | Novel 2‐amino‐1,3‐thiazole‐5‐carboxylates have been synthesised in high yield by unprecedented ultrasonic and thermally mediated nucleophilic displacement of bromide from ethyl 2‐bromo‐1,3‐thiazole‐5‐car‐boxylate by primary, secondary and aryl amines. |
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