A New Synthesis of Optically Active 3‐Substituted (3S)‐3,4‐Dihydro‐5‐(perfluoroalkyl)‐2H‐[1,4]oxazepin‐7‐ones |
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| Authors: | S bastien Richard,Gildas Pri ,Alain Guignard,J r me Thibonnet,J.‐Luc Parrain,Alain Duchê ne,Mohamed Abarbri |
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| Affiliation: | Sébastien Richard,Gildas Prié,Alain Guignard,Jérôme Thibonnet,J.‐Luc Parrain,Alain Duchêne,Mohamed Abarbri |
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| Abstract: | Optically active (perfluoroalkyl)‐oxazepin‐7‐ones were synthesized in two steps starting from ethyl perfluorobut‐2‐ynoate by direct addition of optically active amino alcohols via intermolecular Michael addition and lactone formation. |
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