Neutron diffraction evidence for substrate-triggered intermolecular interactions in the ribosomal protein IF-2 |
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| Affiliation: | 1. Institute for Nursing and Interprofessional Research, Children''s Hospital Los Angeles, Los Angeles, California;2. Pediatric Blood and Marrow Transplant and Cellular Therapy, Children''s Hospital of Colorado, Aurora, Colorado;3. Pediatric Stem Cell Transplantation and Cellular Therapy Program, Ann & Robert H. Lurie Children''s Hospital of Chicago, Chicago, Illinois;4. Texas Children''s Cancer and Hematology Centers Palliative Care Program, Texas Children''s Hospital, Houston, Texas;1. State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, China;2. Key Laboratory for Water and Sediment Sciences, Ministry of Education, School of Environment, Beijing Normal University, Beijing 100875, China;3. Key Laboratory of Tibetan Environment Changes and Land Surface Processes, Institute of Tibetan Plateau Research, Chinese Academy of Sciences, Beijing 100101, China;4. Biology Department, San Diego State University, San Diego, CA, USA |
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| Abstract: | Small-angle neutron scattering experiments provide evidence for substrate-triggered intermolecular correlations between ribosomal protein molecules. The long-range interactions, very likely electrostatic in nature are postulated to be of biological relevance in the transmission of the genetic message. |
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