Synthesis of alkyl 4-alkyl-2-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylates as peptidomimetic building blocks |
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| Authors: | Petra &Scaron tefani?Katja Turn&scaron ek,Danijel Kikelj |
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| Affiliation: | Faculty of Pharmacy, University of Ljubljana, Ašker?eva 7, 1000 Ljubljana, Slovenia |
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| Abstract: | A general synthesis of new alkyl 4-alkyl-2-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate peptidomimetic building blocks from the corresponding alkyl 3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylates through carbanion oxidation is described. |
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| Keywords: | carbanion oxidation 1,4-benzoxazine-2-carboxylates peptidomimetic building blocks |
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