N-(Diethoxyphosphoryl)-O-benzylhydroxylamine—a convenient substrate for the synthesis of N-substituted O-benzylhydroxylamines |
| |
Authors: | Katarzyna B?a?ewskaTadeusz Gajda |
| |
Institution: | Institute of Organic Chemistry, Technical University of Lodz (Politechnika), ?eromskiego Street 116, 90-924 Lodz, Poland |
| |
Abstract: | Easily available N-(diethoxyphosphoryl)-O-benzylhydroxylamine was shown to be convenient, orthogonally protected substrate for regioselective N-alkylation by means of diverse halides under basic conditions (sodium hydride/tetrabutylammonium bromide). An efficient procedure for dephosphorylation of N-substituted N-(diethoxyphosphoryl)-O-benzylhydroxylamine to provide N-substituted O-benzylhydroxylamines was also established. |
| |
Keywords: | hydroxylamines N-alkylation N-(diethoxyphosphoryl)-O-benzylhydroxylamine |
本文献已被 ScienceDirect 等数据库收录! |