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Enantioselective synthesis of chromenes
Authors:Christophe HardouinLise Burgaud  Alain ValleixEric Doris
Institution:CEA/Saclay, Service de Marquage Moléculaire et de Chimie Bioorganique, Département de Biologie Joliot-Curie, 91191 Gif sur Yvette Cedex, France
Abstract:A concise approach for the synthesis of optically active chromenes is reported. The process described herein involves, as the key steps, a Sharpless-epoxidation, a selective deoxygenation, and a ring-closing metathesis.
Keywords:chromene  metathesis  Sharpless-epoxidation  titanium
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