Calixarene amino acids; building blocks for calixarene peptides and peptide-dendrimers |
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Authors: | Heng XuGary R Kinsel Jiang ZhangMeiling Li Dmitry M Rudkevich |
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Institution: | Department of Chemistry and Biochemistry, University of Texas at Arlington, Box 19065, Arlington, TX 76019-0065, USA |
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Abstract: | A modular strategy towards receptor macromolecules is presented, which combines synthetically diverse peptide synthesis with highly functional calixarene chemistry. The design and synthesis of calix4]arene amino acids 1a-f, calix-lysines, is described, which were used as construction blocks to assemble nanoscale, multivalent entities—calix-peptides 2 and calix-peptide-dendrimers 3. |
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Keywords: | calixarenes dendrimers host compounds supramolecular chemistry |
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