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A novel 29-nor-3,4-seco-friedelane triterpene and a new guaiane sesquiterpene from the roots of Phyllanthus oxyphyllus |
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| Authors: | Somyote Sutthivaiyakit Narissara Na NakornWolfgang Kraus Pakawadee Sutthivaiyakit |
| Affiliation: | a Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Ramkhamhaeng Road, Hau mark, Bangkok 10240, Thailand b Department of Chemistry, University of Hohenheim, Stuttgart D-70593, Germany c Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok 10903, Thailand |
| Abstract: | An unusual 29-nor-3,4-seco-friedelan-4(23),20(30)-dien-3-oic acid and a new 5-hydroxy-6,9-epoxyguaiane have been isolated along with other rare terpenes and lignans from Phyllanthus oxyphyllus roots. Their structures were elucidated from spectroscopic data. The radical scavenging properties of some of these compounds were evaluated. seco-Isolariciresinol showed strong antioxidant activity (IC50 0.017±0.001 mM). |
| Keywords: | Phyllanthus oxyphyllus Euphorbiaceae friedelane guaiane cleistanthane lignans antioxidant |
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