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Stereoselective synthesis of β-functionalized α-aminophosphonates via aziridinium ions
Authors:Dorota G PiotrowskaAndrzej E Wró  blewski
Affiliation:Bioorganic Chemistry Laboratory, Faculty of Pharmacy, Medical University of ?ód?, 90-151 ?ód?, Muszyńskiego 1, Poland
Abstract:1,2-Diamino-, 1-amino-2-hydroxy- and 1-amino-2-chloro-2-phenylethylphosphonates were obtained in a stereo- and regioselective manner from 2-amino-1-hydroxy-2-phenylethylphosphonate through the intermediacy of an aziridinium ion.
Keywords:aziridines   phosphonic acids and derivatives   regiospecificity   stereospecificity
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