Synthetic study on indolic enamides |
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Authors: | Kouji KuramochiYuko Osada Takeshi Kitahara |
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Institution: | Department of Applied Biological Chemistry, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan |
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Abstract: | We report a facile method for preparing enamides, based on the Curtius rearrangement and acylation of alkenylcarbamate. Using this approach, total syntheses of coscinamides, chondriamides, and igzamide were achieved. |
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Keywords: | indolic enamides Curtius rearrangement acylation |
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