A novel and environment-friendly method for preparing dihydropyrano[2,3-c]pyrazoles in water under ultrasound irradiation |
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Authors: | Zou Yi Wu Hui Hu Yu Liu Hai Zhao Xuan Ji Honglou Shi Daqing |
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Affiliation: | Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, PR China. |
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Abstract: | A green and convenient approach to the synthesis of dihydropyrano[2,3-c]pyrazoles via four-component reaction of aromatic aldehydes, hydrazine, ethyl acetoacetate and malononitrile in water under ultrasound irradiation is described. This method provides several advantages such as environmental friendliness, shorter reaction time, excellent yields, and simple workup procedure. |
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