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A novel and environment-friendly method for preparing dihydropyrano[2,3-c]pyrazoles in water under ultrasound irradiation
Authors:Zou Yi  Wu Hui  Hu Yu  Liu Hai  Zhao Xuan  Ji Honglou  Shi Daqing
Institution:Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, PR China.
Abstract:A green and convenient approach to the synthesis of dihydropyrano2,3-c]pyrazoles via four-component reaction of aromatic aldehydes, hydrazine, ethyl acetoacetate and malononitrile in water under ultrasound irradiation is described. This method provides several advantages such as environmental friendliness, shorter reaction time, excellent yields, and simple workup procedure.
Keywords:
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