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Visible‐Light‐Induced Direct Photocatalytic Carboxylation of Indoles with CBr4/MeOH |
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| Authors: | Qing‐Qing Yang Marianna Marchini Prof. Dr. Wen‐Jing Xiao Prof. Dr. Paola Ceroni Prof. Dr. Marco Bandini |
| Affiliation: | 1. Department of Chemistry ?G. Ciamician“, Alma Mater Studiorum, University of Bologna, Via Selmi 2, 40126 Bologna (Italy) http://www.mbandini‐group.com;2. Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University (CCNU), 152 Luoyu Road, Wuhan, Hubei 430079 (China) |
| Abstract: | Photocatalysis enables the cascade reactions of indoles and CBr4 in MeOH through a C(sp2)?H functionalization/methanolysis sequence. The title reaction provides an efficient access to indole 2‐ and 3‐carboxylates in a single operation (no preinstallation of protecting as well as directing groups was required) with good yields under mild reaction conditions. |
| Keywords: | carboxylation indole functionalization methanolysis photocatalysis visible light |