Cobalt(III)‐Catalyzed CH/NO Functionalizations: Isohypsic Access to Isoquinolines |
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| Authors: | Hui Wang Julian Koeller Weiping Liu Prof?Dr Lutz Ackermann |
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| Institution: | Institut für Organische und Biomolekulare Chemie, Georg‐August‐Universit?t G?ttingen, Tammannstra?e 2, 37077 G?ttingen (Germany) http://www.ackermann.chemie.uni‐goettingen.de/ |
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| Abstract: | C?H/N?O functionalizations by cobalt(III) catalysis allowed the expedient synthesis of a broad range of isoquinolines. Thus, internal and challenging terminal alkynes proved to be viable substrates for an isohypsic annulation, which was shown to proceed by a facile C?H cobaltation. |
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| Keywords: | alkyne C H activation cobalt isoquinoline N‐O cleavage |
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