|
|||||
|
|
Cover Picture: A Versatile Approach to CF3‐Containing 2‐Pyrrolidones by Tandem Michael Addition–Cyclization: Exemplification in the Synthesis of Amidine Class BACE1 Inhibitors (Chem. Eur. J. 33/2015) |
|
| Authors: | Dr. Natalia Mateu Myriam Ciordia Dr. Oscar Delgado Dr. María Sánchez‐Roselló Dr. Andrés A. Trabanco Dr. Michiel Van Gool Dr. Gary Tresadern Laura Pérez‐Benito Prof. Dr. Santos Fustero |
| Affiliation: | 1. Departamento de Química Orgánica, Universidad de Valencia, 46100‐Burjassot (Spain);2. Laboratorio de Moléculas Orgánicas, Centro de Investigación Príncipe Felipe (CIPF), 46012‐Valencia (Spain);3. Neuroscience Medicinal Chemistry Department, Janssen Research and Development, E‐45007‐Toledo (Spain);4. Departamento de Química y Bioquímica, Facultad de Farmacia Universidad CEU San Pablo, Urbanización Monteprincipe Ctra., Boadilla del Monte Km 5,3, 28668 Madrid (Spain) |
| Abstract: | |
| Keywords: | cyclization drug discovery enzymes fluorine inhibitors |