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A chemo-enzymatic route to enantiomerically pure cyclic tertiary amines
Authors:Dunsmore Colin J  Carr Reuben  Fleming Toni  Turner Nicholas J
Affiliation:School of Chemistry, University of Edinburgh, King's Buildings, West Mains Road, Edinburgh, EH9 3JJ, U.K.
Abstract:Deracemization of racemic chiral tertiary amines has been achieved by combination of an enantioselective amine oxidase, obtained through directed evolution, and ammonia borane in a one-pot process.
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