Aromatization with dearylation on Hantzsch cyclocondensation of 4-(dimethylamino)benzaldehyde,cyclohexane-1,3-diones,and some 1,3-[N,C]dinucleophiles

The Hantzsch three-component cyclization of 4-(dimethylamino)benzaldehyde, cyclohexane-1,3-diones, and some 1,3-N,C]-dinucleophiles (5-amino-3-methyl-1-phenylpyrazole, 3,5-dimethoxyaniline, and 4-amino-1,3-dimethylpyrimidine-2,6-dione) proceeds in boiling acetic acid with the splitting off N,N-dimethylaniline and the formation of polycondensed heterocyclic sytems with a γ-unsubstituted pyridine ring (pyrazolo3,4-b]quinoline, acridine, and pyrimido4,5-b]quinoline). Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 244-251, February, 2009.