Stability of porphyrin-calix[4]arene complexes analyzed by electrospray ionization mass spectrometry |
| |
Authors: | Arai Satoshi Ishihara Shinsuke Takeoka Shinji Ohkawa Haruki Shibue Toshimichi Nishide Hiroyuki |
| |
Affiliation: | Department of Applied Chemistry, School of Science and Engineering, Waseda University, 3-4-1 Okubo, Shinjuku, Tokyo 169-8555, Japan. |
| |
Abstract: | The stability of some porphyrin-calix[4]arene sodium-ion complexes were determined by a collision-activated decomposition (CAD) method utilizing electrospray ionization mass spectrometry (ESI-MS). Comparing the values of E(1/2), the collision energy at which the relative intensity of the complex ion is 0.5, we found that the porphyrin-calix[4]arene complex with the higher value of E(1/2) corresponded to that with the larger association constant (Kass), as measured by 1H-NMR in CDCl3. Both our ESI-MS and NMR studies proved that the number of hydrogen bonds and the rigidity of the calix[4]arene stabilized the complex. The ESI-MS technique could be successful in screening the binding affinity in host-guest systems with a small amount of sample. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|