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Phase Transition,Ordering and Lateral Diffusion in Phospholipid Bilayers in the Presence of Poly(Ethylene Oxide)
Authors:Andrey Filippov  Bulat Munavirov  Oleg N Antzutkin
Institution:1. Institute of Physics, Kazan (Volga Region) Federal University, 420008 Kazan, Russian Federation;2. Chemistry of Interfaces, Luleå University of Technology, SE-97187 Luleå, Sweden;3. Department of Physics, Warwick University, CV4 7AL Coventry, UK
Abstract:The thermal behaviour, molecular orientation and lateral diffusion in the bilayered systems of dimyristoylphosphatidylcholine (DMPC) in the presence of poly(ethylene oxide) (PEO) were studied by NMR and DSC techniques, and it was found that PEO decreases the melting temperature (of vesicles and flat multibilayers) and affects the degree of orientation of DMPC molecules relative to the bilayer normal, but it does not influence the lateral diffusion of DMPC molecules.
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