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Synthesis of 2-amino-5,5-dialkyl-4-arylmethylidene-2-oxazolines from 2-alkyl-4-arylbut-3-yn-2-ols and guanidine |
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| Authors: | Denis S. Baranov Aleksey A. Ryabichev Victor I. Mamatyuk Yurii V. Gatilov Victor G. Kartsev Sergei F. Vasilevsky |
| Affiliation: | 1. Institute of Chemical Kinetics and Combustion, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russian Federation;2. N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 630090 Novosibirsk, Russian Federation;3. InterBioScreen Ltd., 119019 Moscow, Russian Federation |
| Abstract: | Reaction between 2-alkyl-4-arylbut-3-yn-2-ols and guanidine in refluxing pyridine affords 2-amino-5,5-dialkyl-4-arylmethylidene-2-oxazolines. |
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