Law of genome evolution direction: Coding information quantity grows

The problem of the directionality of genome evolution is studied. Based on the analysis of C-value paradox and the evolution of genome size, we propose that the function-coding information quantity of a genome always grows in the course of evolution through sequence duplication, expansion of code, and gene transfer from outside. The function-coding information quantity of a genome consists of two parts, p-coding information quantity that encodes functional protein and n-coding information quantity that encodes other functional elements. The evidences on the law of the evolutionary directionality are indicated. The needs of function are the motive force for the expansion of coding information quantity, and the information quantity expansion is the way to make functional innovation and extension for a species. Therefore, the increase of coding information quantity of a genome is a measure of the acquired new function, and it determines the directionality of genome evolution.