Standard reference materials (SRM's) for measuring genetic damage |
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| Authors: | David S Bergtold Eric Holwitt and Michael G Simic |
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| Institution: | (1) National Institute of Standards and Technology, 20899 Gaithersburg, MD, USA |
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| Abstract: | Summary Standard reference materials were designed for the measurement of radiolytic products resulting from OH radical reaction with DNA in patients treated by radiation therapy. Deuterated thymine glycol and thymidine glycol are proposed as such SRM's; the synthesis of the former is described in detail. They might be of importance for optimising the therapy. |
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