Enantioselective hydrolysis of N-acylated alpha-amino esters at a biphasic interface: tandem reaction kinetic resolution using a chiral complexing agent |
| |
| Authors: | Snyder Seth E Pirkle William H |
| |
| Affiliation: | School of Chemical Sciences, University of Illinois at Urbana-Champaign, 61801, USA. sesnyder@uiuc.edu |
| |
| Abstract: | [reaction: see text] Highly enantioselective hydrolytic kinetic resolutions of esters derived from N-acylated alpha-amino acids proceed rapidly at hydrocarbon/water interfaces in the presence of a proline-derived chiral selector. When performed in tandem with an enantioselective biphasic esterification reaction, esters of 100% enantiomeric excess are obtained |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
