Difluoroalkylamines from high temperature vapor phase reactions of nitrogen trifluoride with alkanes, ethers and benzene |
| |
Authors: | Randolph K. Belter |
| |
Affiliation: | Y-Not Chemical Consulting, Zachary, LA, 70791, United States |
| |
Abstract: | At temperatures around 400 °C, nitrogen trifluoride (NF3) readily reacts with alkanes and benzene as well as ethers. In all cases, products were N,N-difluoroamines. This is in contrast to difluoroamination of benzylic substrates where the initial N,N-difluoroamines underwent eliminations or rearrangements and were not isolated. Cyclic and acyclic alkanes generated N,N-difluoroaminoalkanes. Benzene substituted on the ring to form N,N-difluoroaniline. Ethers reacted to generate α-N,N-difluoroamino ethers. Little direct fluorination was observed. |
| |
Keywords: | Nitrogen trifluoride Alkyl substitution Aromatic substitution Radical abstraction Difluoroalkylamines |
本文献已被 ScienceDirect 等数据库收录! |
|