Chiral silica-based monoliths in chromatography and capillary electrochromatography |
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| Authors: | Dorothee Wistuba |
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| Affiliation: | Institute of Organic Chemistry, University of Tübingen, 72076 Tübingen, Germany |
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| Abstract: | Chiral-modified silica-based monoliths have become well-established stationary phases for both high performance liquid chromatography (HPLC) and capillary electrochromatography (CEC). The silica-based monoliths were fabricated either in situ in the capillaries for nano-HPLC and CEC or in a mould for “conventional” HPLC. The present review summarizes the chiral modification of silica monoliths and the recent development in the field of enantioselective separations by nano-HPLC and CEC. |
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| Keywords: | Monolith CEC Chromatography Enantiomeric separation Enantioselectivity Chiral |
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