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Electrochemical Palladium‐Catalyzed Intramolecular C—H Amination of 2‐Amidobiaryls for Synthesis of Carbazoles
Authors:Qingqing Wang  Xiaojing Zhang  Pan Wang  Xinlong Gao  Heng Zhang  Aiwen Lei
Abstract:The synthesis of carbazoles based on the electrochemical Pd‐catalyzed intramolecular C—H amination of 2‐amidobiaryls through oxidative cross coupling has been achieved under mild reaction conditions. The reaction can be carried out in undivided cell without the addition of external chemical oxidant. Besides good functional group compatibility, the desired carbazoles can be scaled up and modified easily. Compared with previous methods, this protocol affords a simple and sustainable avenue for the construction of carbazoles.
Keywords:Electrosynthesis  Palladium‐catalyzed  Cross coupling  Amination  Carbazoles
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