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Harvesting canthinones: identification of the optimal seasonal point of harvest of Zanthoxylum chiloperone leaves as a source of 5-methoxycanthin-6-one |
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| Authors: | Gerardo Cebrián-Torrejón Landry Kablan Maria Elena Ferreira David Rodríguez de la Cruz Antonio Doménech-Carbó Ninfa Vera de Bilbao |
| Institution: | 1. Laboratoire de Pharmacognosie associé au CNRS, UMR 8076 BioCIS, LabEx LERMIT, Faculté de Pharmacie, Université Paris-Sud, 5, Rue J.-B. Clément, 92296 Chatenay-Malabry, Francegerardo.cebrian@usp.br;3. Laboratoire de Pharmacognosie associé au CNRS, UMR 8076 BioCIS, LabEx LERMIT, Faculté de Pharmacie, Université Paris-Sud, 5, Rue J.-B. Clément, 92296 Chatenay-Malabry, France;4. Department of Tropical Medicine, Casilla de Correo 2511, Instituto de Investigaciones en Ciencias de la Salud Asunción, Universidad Nacional de Asunción, Asuncion, Paraguay;5. Hispano-Luso Agrarian Research Centre (CIALE), University of Salamanca, Río Duero-12, 37185 Villamayor (Salamanca), Spain;6. Departmento de Química Analítica, Universidad de Valencia, Dr. Moliner, 50, 46100 Burjasot (Valencia), Spain |
| Abstract: | This article is focused on the seasonal variation in the contents of 5-methoxycanthin-6-one from the leaves of Zanthoxylum chiloperone (Rutaceae). Based on the pharmacological interest presented by 5-methoxycanthin-6-one, its seasonal variation in Z. chiloperone leaves was analysed in order to determine the best time for harvesting, optimising the 5-methoxycanthin-6-one content. The seasonal dynamics of canthinone alkaloids can be the key to improve the isolation from natural sustainable sources, such as leaves. Complementarily, this study describes the phytochemistry of leaf from this Ruraceae species. |
| Keywords: | phytochemistry seasonality sustainability HPLC–UV–MS MS–MS electrochemistry Rutaceae Zanthoxylum chiloperone alkaloids canthinone benzylisoquinoline alkylamide |