Two new compounds from cultures of the basidiomycete Antrodiella albocinnamomea |
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| Authors: | Zi-Ming Chen Shun-Lin Wang |
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| Affiliation: | 1. School of Chemistry and Chemical Engineering, Lingnan Normal University, Zhanjiang 524048, P.R. Chinachenzm818@163.com;3. School of Information Science and Technology, Lingnan Normal University, Zhanjiang 524048, P.R. China |
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| Abstract: | A new linear triterpene (1), and a new sesquiterpene (2), together with a known compound methyl indole-3-carboxylate (3) were isolated from the crude extract of Antrodiella albocinnamomea. The structures of the new compounds 1–2 were determined by comprehensive spectroscopic analysis. Compound 1 exhibited signi?cant inhibitory activities against protein tyrosine phosphatase 1B (PTP1B) with IC50 value of 1.0 μg/mL. |
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| Keywords: | Antrodiella albocinnamomea linear triterpene sesquiterpene protein tyrosine phosphatase 1B |
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