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High spatial resolution imaging mass spectrometry and classical histology on a single tissue section
Authors:Deutskens Fabian  Yang Junhai  Caprioli Richard M
Affiliation:Department of Biochemistry, Mass Spectrometry Research Center, Vanderbilt University, Nashville, TN, USA.
Abstract:The work presented in this report describes and demonstrates a protocol for protein imaging analysis of biological tissue using MALDI IMS where histological staining and MS analysis are performed on the same tissue section. Spatial image resolution is shown at 35 μm for sagittal sections of the cerebellum from rat brain.
Keywords:MALDI‐MS  imaging mass spectrometry  histology  high resolution  tissue  protein
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