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A short synthesis of 4-amino-3-hydroxybutyric acid (GABOB) via allyl cyanide
Authors:Mete  E.  Maraş   A.  Seçen  H.
Affiliation:(1) Department of Chemistry, Faculty of Arts and Sciences, Ataturk University, 25240 Erzurum, Turkey
Abstract:4-Amino-3-hydroxybutyric acid was synthesized from allyl cyanide in four steps in an overall yield of 38%. Ultrasonically promoted epoxidation of allyl cyanide with m-chloroperoxybenzoic acid giving oxiranylacetonitrile was used as a key step.
Keywords:4-amino-3-hydroxybutyric acid  GABOB  allyl cyanide  epoxidation  sonification  azides
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