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Bacterial adhesion-resistant poly(2-hydroxyethyl methacrylate) derivative for mammalian cell cultures |
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| Authors: | Sohn Eun-Ho Ahn Jooyeon Bhang Suk Ho Kang Junil Yoon Jeyong Kim Byung-Soo Lee Jong-Chan |
| Affiliation: | Department of Chemical and Biological Engineering, Seoul National University, Seoul, Republic of Korea. |
| Abstract: | In an attempting to find new biomaterials for mammalian cell culture, PHEMA derivatives with ester side groups are synthesized by one-step polymer-analogous reaction. These polymers show excellent antifouling properties against S. epidermidis and P. aeruginosa while their cytotoxicity and proliferation activity for HDF cell are on a similar level as commercially available TCPS. The interesting bioadhesion property is systematically correlated with surface properties of the PHEMA derivatives. |
| Keywords: | antifouling bacterial adhesion cell adhesion and proliferation polymer‐analogous reactions poly(2‐hydroxyethyl methacrylate) derivatives |
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