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Bacterial adhesion-resistant poly(2-hydroxyethyl methacrylate) derivative for mammalian cell cultures
Authors:Sohn Eun-Ho  Ahn Jooyeon  Bhang Suk Ho  Kang Junil  Yoon Jeyong  Kim Byung-Soo  Lee Jong-Chan
Institution:Department of Chemical and Biological Engineering, Seoul National University, Seoul, Republic of Korea.
Abstract:In an attempting to find new biomaterials for mammalian cell culture, PHEMA derivatives with ester side groups are synthesized by one-step polymer-analogous reaction. These polymers show excellent antifouling properties against S. epidermidis and P. aeruginosa while their cytotoxicity and proliferation activity for HDF cell are on a similar level as commercially available TCPS. The interesting bioadhesion property is systematically correlated with surface properties of the PHEMA derivatives.
Keywords:antifouling  bacterial adhesion  cell adhesion and proliferation  polymer‐analogous reactions  poly(2‐hydroxyethyl methacrylate) derivatives
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