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Magnetic hyperthermia: Potentials and limitations
Authors:Mozhdeh Peiravi  Hossein Eslami  Mojtaba Ansari  Hadi Zare-Zardini
Institution:1. Department of Biomedical Engineering, Meybod University, Meybod, Iran;2. Hematology and Oncology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran;3. Medical Nanotechnology and Tissue Engineering Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Abstract:Despite the fact that the magnetic hyperthermia (MH) has been known for more than 75 years, it is still debated in its clinical applications. The generation of a higher temperature at a tumor is called hyperthermia. There is a different of temperature ranges going from 39 to 40 ?°C up to such high temperatures as 80–90 ?°C. However, due to its high potential, MH is used along with nanoparticles as heat intermediaries in the treatment of cancer. Many Magnetic Nanoparticles (MNPs) with several properties and morphological metallic structures have been useful to magnetics hyperthermia therapy. These MNPs are categorized into two groups; magnetic alloy nanoparticles (MANPs) and magnetic metal oxide nanoparticles (MMONPs). The principal challenges of this method are the control of local tumoral temperature and the increase in nanoparticles heating power. The hyperthermia agents derived from magnetic nanoparticles along with magnetic field. In the recent study, hyperthermia thought, dissimilar types of magnetic nanoparticles for hyperthermia, efficacy for cancer therapy, advances, challenges, and future chances have been examined.
Keywords:Magnetic  Hyperthermia  Cancer therapy
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