Molecular Imprinting-Chemiluminescence Determination of Norfloxacin Using a Norfloxacin-Imprinted Polymer as the Recognition Material |
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Authors: | Yunhua He Jiuru Lu Hongge Zhang Jianxiu Du |
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Institution: | (1) School of Chemistry and Materials Science, Shaanxi Normal University, 710062 Xi an, P.R. China |
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Abstract: | A selective molecular imprinting-chemiluminescence method was developed for the determination of norfloxacin by using a norfloxacin-imprinted polymer as recognition material and the Ce(IV)-sodium sulfite-norfloxacin chemiluminescence reaction as the detection system. The chemiluminescence intensity responded linearly to the concentration of norfloxacin within 1.0×10–7 1.0×10–5 mol L–1 with a detection limit of 3×10–8 mol L–1. The relative standard deviation for 5.0×10–7 mol L–1 norfloxacin solution was 2.4% (n = 7). This method was applied to the determination of norfloxacin in urine samples, and the results obtained were satisfactory. |
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Keywords: | : Chemiluminescence analysis molecular imprinted polymer norfloxacin |
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