A copper-catalyzed C-N bond formation involving sp-hybridized carbons. A direct entry to chiral ynamides via N-alkynylation of amides |
| |
| Authors: | Frederick Michael O Mulder Jason A Tracey Michael R Hsung Richard P Huang Jian Kurtz Kimberly C M Shen Lichun Douglas Christopher J |
| |
| Affiliation: | Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, USA. |
| |
| Abstract: | A copper-catalyzed new C-N bond formation involving a sp-hybridized carbon is described here leading to a facile entry for syntheses of chiral ynamides. This direct N-alkynylation of amides should have a significant impact on the future development of synthetic methodologies employing ynamides. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
