FTIR studies of vitamin E-cholesterol-DPPC membrane interactions in CH 2 region |
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| Authors: | Feride Severcan, Ü lkü Baykal . Sü zer |
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| Affiliation: | (1) Department of Biological Sciences, Middle East Technical University, 06531 Ankara, Turkey;(2) Department of Chemistry, Bilkent University, 06533 Ankara, Turkey |
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| Abstract: | Binary and ternary mixtures of  -tocopherol (T), cholesterol and dipalmitoyl phosphatidylcholine (DPPC) in the form of multilamellar liposomes have been investigated by Fourier Transform Infrared Spectroscopy (FTIR). Investigation of frequencies, bandwidths and band shapes of CH2 stretching and scissoring bands indicate that the effect of T is dominant in comparison with cholesterol and T decreases the interaction of cholesterol with phospholipid membranes. |
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