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Reactive Polymer Coatings: A General Route to Thiol‐ene and Thiol‐yne Click Reactions
Authors:Jyun‐Ting Wu  Chi‐Hui Huang  Wei‐Chieh Liang  Yen‐Lin Wu  Jiashing Yu  Hsien‐Yeh Chen
Abstract:Reactive polymer coatings were synthesized via chemical vapor deposition (CVD) polymerization process. These coatings decouple surface design from bulk properties of underlying materials and provide a facile and general route to support thiol‐ene and thiol‐yne reactions on a variety of substrate materials. Through the reported technique, surface functions can be activated through a simple design of thiol‐terminated molecules such as polyethylene glycols (PEGs) or peptides (GRGDYC), and the according biological functions were demonstrated in controlled and low‐fouling protein adsorptions as well as accurately manipulated cell attachments.
Keywords:chemical vapor deposition  click chemistry  reactive polymer coatings  thiol‐ene coupling  thiol‐yne coupling
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