| The Regulation Effect of Phosphoryl Group on Amino Acid Side Chain |
| |
| 作者姓名： | 赵玉芬 李艳梅 尹应武 李援朝 |
| |
| 作者单位： | Department of Chemistry，Tsinghua Uniuersity Beijing 100084，PRC，Department of Chemistry，Tsinghua Uniuersity Beijing 100084，PRC，Department of Chemistry，Tsinghua Uniuersity Beijing 100084，PRC，Department of Chemistry，Tsinghua Uniuersity Beijing 100084，PRC |
| |
| 基金项目： | This work was supported by the National Natural Science Foundation of China, the National Science and Technology Committee of China and Tsinghua University, and the Chinese National Educational Ministry Special Grant for YFZ (1990, 1992). |
| |
| 摘 要： | The amino acids' side chains act as the relay device to modulate the chemical reactivity of the N-phosphoryl amino acids. The N-dialkyl phosphoryl cysteine is stable, but the N-dialkyl phosphoryl serine or threoine was converted into many kinds of products at 40℃. The N-dialkyl phosphoryl gltamic acid is a stable compound, while the N-dislkyl phosphoryl aspartic acid was transferred into the peptides, esters and the phosphoryl ester-exchanged products under mild conditions. The N-dialkyl phosphoryl histidine has the similar reactivity through the co-participation of the side chain, carboxyl and phosphoryl groups. A hexacoordinate phosphorus was proposed to account for this differentiation and promotion effect.
|
The Regulation Effect of Phosphoryl Group on Amino Acid Side Chain |
| |
| ZHAO Yu-Fen LI Yan-Mei YIN Ying-Wu and LI Yuan-Chao.The Regulation Effect of Phosphoryl Group on Amino Acid Side Chain[J].Science in China(Chemistry),1993(12). |
| |
| Authors: | ZHAO Yu-Fen LI Yan-Mei YIN Ying-Wu and LI Yuan-Chao |
| |
| Abstract: | |
| |
| Keywords: | N-phosphoryl amino acid amino acid aide chain's regulation effect partieipation of phosphoryl group hexaeoordinate phosphorus |
| 本文献已被 CNKI 等数据库收录！ |
