Advances in Microfluidic Biosensors Based on Luminescent Bacteria |
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Authors: | Xiao-Wei JIN Zhe-Yu LI Pian-Pian XU Xiao-Yan ZHANG Nan-Qi REN Vitaliy V Kurilenko Kai SUN |
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Institution: | 1. State Key Laboratory of Urban Water Resource and Environment, School of Environment, Harbin Institute of Technology, Harbin 150090, China;2. Institute of Earth Sciences, Saint-Petersburg State University, Saint-Petersburg 199034, Russian Federation |
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Abstract: | Luminescent bacteria can emit visible light at 450–490 nm, and its luminous intensity decreases with the increase of the concentration of toxic substances in test solution. The method using luminescent bacteria is widely used in acute toxicity analysis of water quality because it is a simple, rapid and low-cost way. In recent years, biosensors based on luminescent bacteria have attracted more and more attention, and the reports of bioluminescence biosensors based on microfluidic systems are increasing day by day. Based on the characteristics and mechanism of luminescent bacteria, this paper introduces their applications in the environmental monitoring, and summarizes several new bioluminescence sensors. |
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Keywords: | Luminescent bacteria Acute toxicity Environmental pollutant Microfluidic Biosensor Review |
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