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A new xanthone derivative from the co-culture broth of two marine fungi (strain No. E33 and K38)
Authors:Chunyuan Li   Jie Zhang   Changlun Shao   Weijiang Ding   Zhigang She  Yongcheng Lin
Affiliation:(1) Institute of Biomaterial, College of Science, South China Agricultural University, 510642 Guangzhou, P. R. China;(2) School of Medicine and Pharmacy, Ocean University of China, Qingdao, 266003 Qingdao, P. R. China;(3) School of Chemistry and Chemical Engineering, Sun Yat-sen (Zhongshan) University, 510275 Guangzhou, P. R. China;
Abstract:A new xanthone derivative, 8-hydroxy-3-methyl-9-oxo-9H-xanthene-1-carboxylic acid methyl ether (1), was isolated from the co-culture broth of two mangrove fungi (strain No. K38 and E33) isolated from the South China Sea coast. The structure of 1 was determined by comprehensive spectroscopic methods, especially 2D NMR techniques. Primary bioassays showed that compound 1 has inhibitory activity against five microorganisms, including Gloeasporium musae and Peronophthora cichoralearum etc.
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