| Synthesis of a Novel Series of S-Alkyl Thiobenzoate Compounds as Farnesyltransferase Inhibitors |
| |
| 引用本文： | ShengBiaoWAN JunFENG FengMingCHU ZongRuGUO. Synthesis of a Novel Series of S-Alkyl Thiobenzoate Compounds as Farnesyltransferase Inhibitors[J]. 中国化学快报, 2005, 16(2): 151-154 |
| |
| 作者姓名： | ShengBiaoWAN JunFENG FengMingCHU ZongRuGUO |
| |
| 作者单位： | DepartmentofMedicinalChemistry,InstituteofMateriaMedica,ChineseAcademyofMedicalSciences＆PekingUnionMedicalCollege,Beijing100050 |
| |
| 摘 要： | S-akyl thiobenzoate compounds were designed as farnesyltransferase (FTase) inhibitors. An effective synthetic method was explored. The structures of the target compounds were elucidated by NMR spectral and elemental analysis.
|
| 关 键 词： | S-烷基硫代苯甲酸 抑制剂 法呢基转移酶 合成方法 苯并二氮杂草 麻醉剂 |
Synthesis of a Novel Series of S-Alkyl Thiobenzoate Compounds as Farnesyltransferase Inhibitors |
| |
| Sheng Biao WAN,Jun FENG,Feng Ming CHU,Zong Ru GUO?. Synthesis of a Novel Series of S-Alkyl Thiobenzoate Compounds as Farnesyltransferase Inhibitors[J]. Chinese Chemical Letters, 2005, 16(2): 151-154 |
| |
| Authors: | Sheng Biao WAN Jun FENG Feng Ming CHU Zong Ru GUO? |
| |
| Affiliation: | Sheng Biao WAN,Jun FENG,Feng Ming CHU,Zong Ru GUO? Department of Medicinal Chemistry,Institute of Materia Medica,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing 100050 |
| |
| Abstract: | S-akyl thiobenzoate compounds were designed as farnesyltransferase (FTase) inhibitors.An effective synthetic method was explored. The structures of the target compounds wereelucidated by NMR spectral and elemental analysis. |
| |
| Keywords: | S-Akyl thiobenzoate compounds benzodiazepine farnesyltransferase. |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
