| 摘 要： | Poly(orthoesters)isaclassofbiodegradablepolymersandtheirdegrada-tionratecanbereadilycontrolledbytheincorporationofacidicorbasicexcipi-entsintothepo1ymermatrix[1J.Severaltypes0fbiocompatiblepoly(orthoes-ters)havebeenextensivelyinvestigatedasthecarrierfordrugdeliverysys-tem[2J.However,lessw0rkhasbeendone0nointment-1ikepoly(orthoesters).Asadrugcarrier,theointment-likepoly(orthoesters)hastheadvan-tageofincorporatingtherapeuticagentsatr0omtemperatureandwithouttheuseofsolvents,andisidealf0rthedeliv…
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