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4-羟基喹啉类化合物的合成研究进展
引用本文:茆勇军,何海军. 4-羟基喹啉类化合物的合成研究进展[J]. 化学通报, 2014, 77(10): 950-950
作者姓名:茆勇军  何海军
作者单位:上海工程技术大学 化学化工学院,上海工程技术大学 化学化工学院
摘    要:4-羟基喹啉类[4-hydroxyquinolines或4(1H)quinolones]化合物是一类重要的药物合成中间体,在抗疟、抗癌、抗菌、抗病毒、抗糖尿病等领域发挥重要作用。本文综述了4-羟基喹啉类衍生物的合成方法,包括热环合、碱环合和还原环合等。

关 键 词:4-羟基喹啉类化合物  合成方法
收稿时间:2014-03-09
修稿时间:2014-03-28

Progress in Synthesis of 4-Hydroxyquinoline Derivatives
Mao Yongjun and He Haijun. Progress in Synthesis of 4-Hydroxyquinoline Derivatives[J]. Chemistry, 2014, 77(10): 950-950
Authors:Mao Yongjun and He Haijun
Affiliation:College of Chemistry and Chemical Engineering,Shanghai University of Engineering Science,College of Chemistry and Chemical Engineering,Shanghai University of Engineering Science
Abstract:4-Hydroxyquinoline [or 4 (1H) quinolone] derivatives are important intermediates in pharmaceutical synthesis and play significant roles in antimalarial, anticancer, antibacterial, antiviral and antidiabetic. Progress in synthesis of 4-hydroxyquinoline derivatives, including thermal, basic and reductive cyclization methods, are summarized in this review.
Keywords:4-hydroxyquinoline   synthesis   progress
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